Utilized genetic linkage analysis & candidate gene analysis to identify locus conferring a spontaneous semi-dominant autosomal monogenic mutation causing late-onset ataxia in mouse.
Developed a high-resolution map demarcating the boundaries between congenic DNA segments in
several mouse haplotypes using a panel of novel microsatellite markers.
Trained graduate & undergraduate students in primer design, DNA extraction, PCR, & gel electrophoresis.
Posted @ 01:11PM, September 06, 2007
by Saul Arellano | Permalink
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